DNA analysis is being used to help solve the 18th Century mystery of the origins of an Anglesey (Wales) medical family.
Two boys were sole survivors of a 1745 shipwreck and experts want to find out where in the world they were born.
One of the boys was a brilliant manipulator and healer of bones, and started a family of doctors who helped develop orthopaedic medicine.
Now DNA has been taken from a direct male descendant and scientists hope the mystery will finally be solved.
At the time of the shipwreck the boys were rescued off the Skerries by a smuggler called Dannie Lukie.
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